Lysosomal disruption, mitochondrial impairment, histopathological and oxidative stress in rat's nervous system after exposure to a neonicotinoid (imidacloprid).

Imidacloprid (IMI), a neonicotinoid pesticide, has been widely used due to its high efficiency against insect pests. However, its prolonged exposure may pose significant risks to non-target organisms, including mammals. Recent studies have raised concerns about its potential neurotoxicity, yet the underlying mechanisms remain poorly understood.

Alteration of membrane integrity and respiratory function of brain mitochondria in the rats chronically exposed to a low dose of acetamiprid.

The pesticides are used in several fields of agriculture and farms to protect crops against harmful insects and herbs. The increased and uncontrolled use of these pollutants is very hazardous for the population health. Consumption of contaminated food matrices with these pesticides could impair the cell integrity and its molecular function.

Impairment of mitochondrial integrity and redox status in brain regions during a low-dose long-term exposition of rats to pyrethrinoïds: the preventive effect of quercetin.

Pyrethrinoïds are synthetic pesticides widely used in agriculture and farms to protect crops from weeds, insects, fungi, and molds. Increased and uncontrolled use of these pollutants can have harmful effects on human health via consumption of contaminated food products. In the present study, deltamethrin (DLT = 3.

Effects of Deltamethrin on striatum and hippocampus mitochondrial integrity and the protective role of Quercetin in rats.

The present work is to evaluate the neurotoxicity induced by pyrethroid insecticide "Deltamethrin" at 0.32 mg/kg/day in two main regions of the Wistar rat brain (hippocampus and striatum) and the protective effects of Quercetin at 10 mg/kg/day on this toxicity after 90 days of exposure. The assay of brain parameters showed that Deltamethrin caused a significant increase of mitochondrial metabolite level (proteins, lipids, and carbohydrates) and enzyme activity (glutathione S-transferase and superoxide dismutase); a decreased amount of mitochondrial glutathione level and catalase and glutathione peroxidase activities; and an increase of malondialdehyde (MDA) acid levels of the two regions.

Neurobehavioral deficits and brain oxidative stress induced by chronic low dose exposure of persistent organic pollutants mixture in adult female rat.

Persistent organic pollutants (POPs) are long-lived organic compounds that are considered one of the major risks to ecosystem and human health. Recently, great concerns are raised about POPs mixtures and its potential toxicity even in low doses of daily human exposure. The brain is mostly targeted by these lipophilic compounds because of its important contain in lipids.

The toxicity study of a systemic fungicide: artea 330 EC on the physiology and the respiratory metabolism of the tadpole (Rana saharica).

The intensification of the cereal cultures accompanied by the apparition of damaging illnesses for these cultures. These illnesses are Largely imputed to mushrooms micro and macroscopic chatty of important damages at wheat, the barley and of none targeted other animal species. The products used against these illnesses are called: Fungicides.

The impact of flucycloxuron on eggs weight kinetic and hematological parameters of chicken (Gallus domesticus).

The struggle against the harmful bugs of culture is intensified, and several products are appeared every year without the knowledge how to control their effects on environment and especially on being life. The introduced chemical products in nature are generally, the synthesis products witch are the pesticides. Our study consist the impact mechanism of a pesticides (FCX) on other biological model than harmful bugs, this biological model is a vertebrate model witch is the domestic chicken eggs (Gaollus domesticus).