Publications by authors named "Rachel Perlman"

Article Synopsis
  • Early hominins likely had access to open, grassy areas and may have relied on underground storage organs (USOs) for their diet, particularly during drier seasons.
  • Geladas, a primate species that primarily eats grass, shift their diet to include more USOs when grass is scarce, making them an interesting case study for examining dietary strategies.
  • Research showed that while male geladas increased their movement during dry months, they actually had higher energetic status, suggesting that USOs might be energy-rich rather than fallback foods, indicating potential advantages in their consumption for early hominin diets.
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Green stormwater infrastructure (GSI) is adopted to reduce the impact of stormwater on urban flooding and water quality issues. This study assessed the performance of GSI, like bioretention basins, in accumulating metals. Twenty one GSI basins were considered for this study, which were located in New York and Pennsylvania, USA.

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As the worst global pandemic of the past century, coronavirus disease 2019 (COVID-19) has had a disproportionate effect on maintenance dialysis patients and their health care providers. At a virtual roundtable on June 12, 2020, Dialysis Outcomes and Practice Patterns Study (DOPPS) investigators from 15 countries in Asia, Europe, and the Americas described and compared the effects of COVID-19 on dialysis care, with recent updates added. Most striking is the huge difference in risk to dialysis patients and staff across the world.

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Article Synopsis
  • - The study investigates how gut microbiome composition in wild Ethiopian geladas adapts to seasonal changes in food availability and environmental conditions, analyzing 758 samples to understand these dynamics.
  • - Findings reveal that gut microbial diversity is influenced primarily by rainfall and food type, with certain bacteria thriving in wetter months while others dominate during dryer periods, pointing to a seasonal dietary shift.
  • - Additionally, cold and dry conditions lead to increases in bacterial genes associated with energy and metabolism, suggesting that the gut microbiome plays a crucial role in helping geladas cope with nutritional and thermoregulatory challenges.
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Background: International variation in anemia assessment and management practices in chronic kidney disease (CKD) is poorly understood.

Methods: We performed a cross-sectional analysis of anemia laboratory monitoring, prevalence and management in the prospective Chronic Kidney Disease Outcomes and Practice Patterns Study (CKDopps). A total of 6766 participants with CKD Stages 3a-5ND from nephrology clinics in Brazil, France, Germany and the USA were included.

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Background: Decisions about dialysis for advanced kidney disease are often strongly shaped by sociocultural and system-level factors rather than the priorities and values of individual patients. We examined international variation in the uptake of conservative approaches to the care of patients with advanced kidney disease, in particular discontinuation of dialysis.

Methods: We employed an observational cohort study design using data collected from patients maintained on long-term hemodialysis between 1996 and 2015 in facilities across 12 developed countries participating in the Dialysis Outcomes and Practice Patterns Study (DOPPS).

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Rationale & Objective: Peritoneal dialysis (PD) is a home-based kidney replacement therapy used by a growing number of patients with kidney failure. This qualitative study explores the impact of remote management technologies on PD treatment priorities of patients, their care partners, and clinicians.

Study Design: Qualitative study, designed and conducted in collaboration with a stakeholder panel that included patients, patient advocates, care partners, and health care professionals.

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Article Synopsis
  • The study examined anemia management in peritoneal dialysis (PD) patients across six countries, revealing differences in hemoglobin levels and treatment practices.
  • Use of erythropoiesis-stimulating agents (ESAs) was significantly higher in Japan compared to other countries, while the US showed notably higher ferritin levels and intravenous (IV) iron use.
  • Overall, despite similar hemoglobin ranges, the research highlighted international variations in treatment approaches for managing anemia in PD patients.
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Background: There is a paucity of information on kidney education and screening programs in Indian youth.

Methods: Participants (n=2,158) from Chennai colleges were educated about the kidneys and chronic kidney disease (CKD) and screened in a pilot program from April to May 2013. This entailed: 1) a presentation and educational video and 2) an on-site assessment of weight, blood pressure, and demographic information.

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Objectives: Reproductive skew is proposed to link to despotism in dominance hierarchies. While studies illustrating male skew are plentiful, demonstrating the link to despotism is rare. Likewise, it is often unknown which factors (e.

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In species with strong male-male competition, access to females in multimale-multifemale groups is usually regulated via a dominance hierarchy. The highest ranking (alpha) male often has priority of access and sires most offspring. The alpha male can change in three basic ways: (i) a recent immigrant or a resident challenges and becomes the new alpha; (ii) formation of a new group; (iii) succession-becoming alpha after higher ranking males have left.

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Purpose: Physicians and their spouses experience challenges to their relationships, some of which are shared with the general population and others of which are unique to the field of medicine. Trainees and junior faculty members remain curious about how they will balance their careers alongside marriage and family obligations. This study explores the challenges and strengths of dual- and single-physician relationships.

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Kidney transplantation is currently the best treatment for end-stage renal disease, both in terms of mortality benefit and quality of life (QOL). Elderly patients are a rapidly growing subset of the kidney transplant waiting list. While it is clear that elderly individuals have a mortality benefit from kidney transplant, it is less clear how to make sure these individuals benefit from optimal QOL following transplant.

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Portfolios are emerging as a tool for documenting learning progression and assessing competency. ePortfolios are appealing as a portable and fluid means of documenting both learning and relevant experiences in a large number of students. Competence and learning can be especially difficult to document in important aspects of education and training, such as patient-centeredness, the cultural context of disease, and social determinants of health that do not lend themselves to fact-based assessment methods.

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Background: Amiodarone is a class III antiarrhythmic agent that is widely used in the treatment of a variety of arrhythmias. Several different systemic side effects are reported after use of this medication. In this article, we report a case that had developed syndrome of inappropriate antidiuretic hormone (SIADH) after starting treatment with this agent.

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Purpose: To use qualitative analysis of interview transcripts with clinician-educators who facilitate small-group discussions on psychosocial themes--including doctoring--to answer the question, "What impact does facilitating small-group discussions of the patient's experience with chronic illness, the doctor-patient relationship, and doctoring have on faculty instructors' attitudes regarding their roles as clinicians and teachers?"

Method: In 2006, in-depth, face-to-face interviews using an open-ended question format were conducted with individual faculty small-group instructors teaching in the Family Centered Experience and Longitudinal Case Studies courses at the University of Michigan Medical School. Interview transcripts were analyzed using grounded theory methodology to identify emerging themes. Accuracy of interpretations and saturation of themes was confirmed by repeated contextual reading of the transcripts.

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