Publications by authors named "Rachel N Tavory"
Article Synopsis
- * Researchers studied animals with combinations of these genetic changes, leading to an increase in certain B cells within the spleen that exhibited traits similar to the MCD subtype.
- * The study suggests that these altered B cells, which show signs of self-reactivity and specific dependency on certain proteins, may represent an early form of the cancer, providing insights into its development.
In eukaryotes, the most common epigenetic DNA modification is methylation of carbon 5 of cytosines, predominantly in CpG dinucleotides. Methylation patterns are established and maintained by a family of proteins known as DNA methyltransferases (DNMTs). DNA methylation is an important epigenetic mark associated with gene repression, and disruption of the normal DNA methylation pattern is known to play a role in several disease states.
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