Physical properties and biocompatibility effects of doping SiO and TiO into phosphate-based glass for bone tissue engineering.

Phosphate glass is continuing to gain more attention as potential bone substitutes. The ternary (PO-CaO-NaO) is investigated in terms of both physical properties and biocompatibility by doping different percentages of SiO and TiO. Two groups were prepared; the first has different percentages of TiO and SiO, whereas the second group compositions have 5 mol% TiO and 5 mol% SiO being added to compensate the network-forming oxide PO and the network-modifying oxide CaO.