Resistance training and pioglitazone lead to improvements in muscle power during voluntary weight loss in older adults.

Background: The prevalence of obesity in older adults is increasing but concerns exist about the effect of weight loss on muscle function. Demonstrating that muscle strength and power are not adversely affected during "intentional" weight loss in older adults is important given the wide-ranging negative health effects of excess adiposity.

Methods: Participants (N = 88; age = 70.