Publications by authors named "Rachel M Lukowicz"
Article Synopsis
- Myopia, a common eye disorder in children, is linked to the GJD2 genetic locus, but its specific role in eye development is not well understood.
- Research in zebrafish shows that removing certain GJD2 gene orthologs (gjd2a and gjd2b) affects eye shape and vision.
- Specifically, depletion of gjd2a causes hyperopia and changes in retinal function, while gjd2b loss leads to cataracts and eye elongation, highlighting their critical roles in eye health.
Article Synopsis
- Colorimetric sensor arrays are emerging as effective tools for identifying and quantifying chemical substances, using data from multiple sensors to analyze various acid and basic samples.
- The study employed chemometric methods like PCA, HCA, and LDA to visualize the data, successfully distinguishing between different analyte clusters and concentrations.
- Results showed that LDA had a high accuracy rate of 95 out of 96 analyte identifications, while KNN and HQI also effectively identified the analytes, with solvent and image effects having no impact on the methods used.
Article Synopsis
- The study investigates the use of RGB image analysis from colorimetric sensor arrays to identify and quantify different chemical analytes, leveraging image analysis software like ImageJ.!
- Nine chemometric methods were evaluated for their effectiveness in classifying various solutions of acetic acid, malonic acid, lysine, and ammonia, with LDA and KNN performing particularly well with over 90% accuracy.!
- This research expands on existing literature by comparing a broader range of chemometric techniques, highlighting that traditional methods such as PCA, LDA, HCA, and KNN are the most commonly used for colorimetric array analysis.
Crit Rev Anal Chem
March 2017
Article Synopsis
- * A unified detection technology that analyzes threats in real-time is essential for effective reconnaissance missions.
- * The review highlights colorimetric sensor arrays, which change colors to indicate the presence of dangerous substances, and discusses future technologies for hazardous substance detection in places like war zones.
