Publications by authors named "Rachel Lea Draelos"

Background: Medical use cases for machine learning (ML) are growing exponentially. The first hospitals are already using ML systems as decision support systems in their daily routine. At the same time, most ML systems are still opaque and it is not clear how these systems arrive at their predictions.

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Understanding model predictions is critical in healthcare, to facilitate rapid verification of model correctness and to guard against use of models that exploit confounding variables. We introduce the challenging new task of explainable multiple abnormality classification in volumetric medical images, in which a model must indicate the regions used to predict each abnormality. To solve this task, we propose a multiple instance learning convolutional neural network, AxialNet, that allows identification of top slices for each abnormality.

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Objectives: To evaluate a machine learning model designed to predict mortality for Medicare beneficiaries aged >65 years treated for hip fracture in Inpatient Rehabilitation Facilities (IRFs).

Design: Retrospective design/cohort analysis of Centers for Medicare & Medicaid Services Inpatient Rehabilitation Facility-Patient Assessment Instrument data.

Setting And Participants: A total of 17,140 persons admitted to Medicare-certified IRFs in 2015 following hospitalization for hip fracture.

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Article Synopsis
  • A comprehensive chest CT data set of 36,316 volumes from nearly 20,000 patients was created, making it the largest multiply-annotated medical imaging data set to date.
  • A rule-based method with a high accuracy (F-score of 0.976) was developed to automatically label abnormalities from free-text radiology reports.
  • A deep convolutional neural network (CNN) model achieved strong classification performance, with an AUROC above 0.90 for 18 abnormalities, and demonstrated that more training labels significantly improved overall model performance.
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