Publications by authors named "Rachel K Berlin"
Gabapentin Therapy in Psychiatric Disorders: A Systematic Review.
Prim Care Companion CNS Disord
February 2016
Article Synopsis
- Gabapentin is often used off-label to treat various psychiatric disorders, but there is ongoing debate regarding its effectiveness.
- A systematic review analyzed literature from 1983 to 2014 and identified 219 relevant studies, out of which only 34 had a strong evidence level related to its use in psychiatric conditions.
- The findings suggest gabapentin might help with some anxiety disorders and could be effective for alcohol withdrawal, but there's insufficient evidence to support its use in treating depression, PTSD, OCD, or certain substance abuses.
Objective: Gabapentin (GBP), originally an antiepileptic drug, is more commonly used in the treatment of pain, including headache disorders. Off-label GBP is used in headache disorders with some success, some failure, and much debate. Due to this ambiguity, a clinical evidence literature review was performed investigating GBP's efficacy in headache disorders.
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