Publications by authors named "Rachel Jia"
Article Synopsis
- The study investigates the incidence and risk factors for heterotopic ossification (HO) following surgical treatment of proximal humeral fractures, highlighting a 15% occurrence rate in the patient sample.
- It identifies male sex and dislocation as significant risk factors for developing HO, while factors like age, injury characteristics, and surgical methods showed no predictive value.
- The findings contribute valuable insights into identifying patients at higher risk for HO following their surgery, paving the way for further research on preventative measures.
"Lipase Only, Please": Reducing Unnecessary Amylase Testing.
Jt Comm J Qual Patient Saf
November 2019
Background: Serum amylase testing is not recommended for the workup of acute pancreatitis; yet it is commonly ordered in acute care settings.
Methods: This was a student-led quality improvement initiative with application of a pre-post study design at two urban hospitals: Mount Sinai Hospital, a 1,134-bed academic hospital, and Mount Sinai Queens, a 235-bed community hospital. The multifaceted intervention combined a targeted educational and awareness campaign with the decoupling of amylase from electronic order sets (at the academic hospital only), as well as a nonintrusive electronic medical record (EMR) advisory statement (at both hospitals).
Context: Several anti-programmed death-1 (anti-PD-1) and anti-programmed death ligand-1 (anti-PD-L1) antibodies have been approved by regulatory authorities for treatment of platinum-resistant metastatic urothelial cancer (mUC). The impact of these therapies on survival, and comparability of PD-1 versus PD-L1 blockade are unknown.
Objective: To determine the restricted mean survival time (RMST) of patients with platinum-resistant mUC treated with PD-1/PD-L1 inhibitors and to compare RMSTs in patients treated with PD-1 versus PD-L1 inhibitors.
Background: Achieving a pathologic complete response (pCR) with neoadjuvant chemotherapy (NAC) in patients with muscle-invasive bladder cancer (MIBC) has been associated with improved overall survival (OS). This study was aimed at evaluating the impact of pathologic downstaging (pDS; ie, a pT stage at least 1 stage lower than the pre-NAC cT stage) on the OS of patients with MIBC treated with NAC.
Methods: The Retrospective International Study of Cancers of the Urothelial Tract (RISC) and the National Cancer Database (NCDB) were queried for cT2-4N0M0 patients treated with NAC.
Purpose: Achieving a pathologic complete response (pCR) with neoadjuvant chemotherapy (NAC) for muscle-invasive bladder cancer (MIBC) is associated with a favorable prognosis. Patients with pathologic residual disease (pRD) generally have poor outcomes. However, prognosis after radical cystectomy (RC) improves with ongoing survivorship.
View Article and Find Full Text PDFBackground: Although radical cystectomy (RC) is a standard treatment for muscle-invasive bladder cancer (MIBC), for many patients the risks versus benefits of RC may favor other approaches. We sought to define the landscape of early postcystectomy mortality in the United States and identify patients at high risk using pretreatment variables.
Methods: We identified patients with MIBC (cT2-T4aN0M0) who underwent RC without perioperative chemotherapy within the National Cancer Database (2003-2012).
Telemedicine-Enabled Clinical Trial of Metformin in Patients With Prostate Cancer.
JCO Clin Cancer Inform
November 2017
Purpose: Clinical trials are critical to informing cancer care but often are hampered by slow accrual and lack of generalizability because of poor geographic accessibility. We tested the feasibility of replacing onsite study visits with telemedicine visits in a prospective clinical trial.
Methods: Castration-naïve patients with prostate cancer and a rising serum prostate-specific antigen after definitive local therapy were eligible.
Purpose: To determine a relationship between sexual functioning and health state among survivors of stage I endometrial cancer, and to examine whether adjuvant intravaginal radiotherapy (IVRT) affects these measures compared to hysterectomy alone.
Methods: Two hundred five survivors (>1 year from surgery) completed questionnaires containing the EuroQol (EQ5D) and the Female Sexual Function Index (FSFI). A total of 136 (66.
Objectives: To evaluate the accuracy of platelet counts from various hematology analyzers using a reference immunologic method.
Methods: We tested 403 samples with platelet counts less than 50 × 10(9)/L with the Advia (Siemens, Tarrytown, NY), Sysmex (Mundelein, IL), and Abbott (Santa Clara, CA) analyzers.
Results: All methods showed a positive bias, especially at less than 20 × 10(9)/L and less than 10 × 10(9)/L.