Context: Whether proton pump inhibitors (PPI) can improve glycemic control among individuals with diabetes or decrease the risk of incident diabetes in the general population is unclear.
Objective: To evaluate the impact of PPI therapy on glycemic control among individuals with diabetes and the risk of diabetes among those without diabetes.
Results: PubMed, Embase, Scopus, and ClinicalTrials.
Background Evidence on the differences in fracture risk associated with non-vitamin K antagonist oral anticoagulants (NOAC) and warfarin is inconsistent and inconclusive. We conducted a systematic review and meta-analysis to assess the fracture risk associated with NOACs and warfarin. Methods and Results We searched PubMed, Embase, Cochrane Library, Scopus, Web of Science, and ClinicalTrials.
View Article and Find Full Text PDFContext: Benefits of thyroid hormone therapy on mortality in adults with subclinical hypothyroidism remain undetermined.
Objective: To summarize the impact of thyroid hormone therapy on mortality in adults with subclinical hypothyroidism.
Data Sources: PubMed, Embase, Scopus, Web of Science, and Clinicaltrials.
Painful Hashimoto thyroiditis (pHT) is a rare diagnosis, and optimal treatment remains unclear. To better characterize pHT, PubMed, Embase, Scopus, and Web of Science indexes were searched for case reports or case series reporting pHT, published between 1951 and February 2019. Seventy cases reported in 24 publications were identified.
View Article and Find Full Text PDFContext: The evidence of whether hypothyroidism increases mortality in the elderly population is currently inconsistent and conflicting.
Objective: The objective of this meta-analysis is to determine the impact of hypothyroidism on mortality in the elderly population.
Data Sources: PubMed, Embase, Cochrane Library, Scopus, and Web of Science databases were searched from inception until May 10, 2019.
Background: Complicated medical therapies traditionally performed in acute care hospitals are increasingly moving to the home, requiring patients and informal caregivers to perform complicated medical tasks. For example, in outpatient parenteral antimicrobial therapy (OPAT), patients and caregivers perform antimicrobial infusions and venous catheter care. The objective of this study was to characterize patient understanding of patient, caregiver, and health care worker roles in OPAT and barriers to fulfilling these roles, with the goal of understanding how to best support patients and their caregivers.
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