Publications by authors named "Rachel H Occhiogrosso"
Article Synopsis
- Tissue-agnostic therapies have broadened treatment options for advanced solid tumor patients, with FDA approvals for pembrolizumab and TRK inhibitors like larotrectinib and entrectinib emphasizing the need for next-generation sequencing (NGS).
- A case study of a 64-year-old woman with triple-negative breast cancer, resistant to multiple treatments, revealed a rare mutation through NGS that enabled effective targeted therapy.
- After being treated with the TRK inhibitor larotrectinib, the patient experienced significant improvements in her condition, highlighting the importance of personalized medicine and NGS in cancer treatment.
Article Synopsis
- Patients with COVID-19 have a higher risk of arterial line thrombosis compared to those with sepsis or ARDS, leading to increased instances of arterial line removal.
- The study utilized a Fine-Gray subdistribution hazard model and identified significant differences in arterial line complications between critically ill COVID-19 patients and those with other severe conditions.
- Results indicated that COVID-19 patients faced a 2.18 times greater risk for arterial line clots, emphasizing the need for careful monitoring and management of arterial lines in this population.
Background: We conducted a feasibility study of integrating a free, online patient health community, PatientsLikeMe (PLM), into the neo/adjuvant care of older patients recently diagnosed with breast cancer. We assessed whether PLM was an appealing social forum to improve women's treatment experience during this stressful and often isolating time.
Patients And Methods: We enrolled women ages ≥60 years with recently diagnosed nonmetastatic invasive breast cancer at a single center.