Background: Creeping indigo (Indigofera spicata) toxicosis is an emerging problem among horses in Florida and bordering states.
Objectives: To quantify the putative toxins l-indospicine (IND) and 3-nitropropionic acid (NPA) in creeping indigo collected from multiple sites and to measure plasma toxin concentrations in ponies fed creeping indigo and horses with presumptive creeping indigo toxicosis.
Study Design: Experimental descriptive study with descriptive observational field investigation.