Vanin-1 expression and methylation discriminate pediatric asthma corticosteroid treatment response.

Background: There is considerable heterogeneity in asthma treatment response.

Objective: We sought to identify biomarkers of corticosteroid treatment response in children with asthma and evaluate the utility and mechanistic basis of these biomarkers.

Methods: Children (5-18 years) presenting to the emergency department with an acute asthma exacerbation were recruited and followed during hospitalization.