Publications by authors named "Rachael J Benson"
Objective: To determine which antiepileptic drugs pregnant women receive by trimester.
Methods: This retrospective cohort study using the IBM Watson Health MarketScan Research Databases evaluated which antiepileptic drugs pregnant women with epilepsy received by trimester. Women with aged 15-54 years with a history of seizure disorder who underwent a delivery hospitalization between 2008 and 2017 were included in the analysis.
Background: Anti-seizure medications (ASMs) are used to treat conditions such as epilepsy and bipolar disorder. Some of these drugs are associated with an increased risk of congenital malformations and adverse developmental outcomes.
Objectives: To examine trends in use of ASMs among pregnant women in the Netherlands according to medication safety profile.
Maternal morbidity and mortality associated with epilepsy.
J Matern Fetal Neonatal Med
December 2022
Article Synopsis
- - The study aimed to evaluate the risks of adverse maternal outcomes during delivery for women with epilepsy, particularly focusing on those who received anti-epileptic drugs (AEDs) before delivery.
- - Findings showed that women with epilepsy on AEDs did not experience an increased risk of mortality, with no deaths reported in this group; however, they faced a higher risk of severe maternal morbidity and other complications like placental abruption and cesarean delivery.
- - The overall conclusion indicates that while the risk of mortality for these women is not significantly elevated, there are modest increases in the risk for other adverse outcomes during delivery compared to women without epilepsy.