Publications by authors named "Rachael Hale"
Article Synopsis
- Scientists are testing if taking prebiotics can help kidney transplant patients avoid infections and feel better in their digestive systems.
- They will have 60 kidney transplant patients take either prebiotics or a fake treatment for about a month and a half.
- The study will look at things like how well patients tolerate the treatment and if it improves their health and quality of life.
Objectives: Modulating the large intestinal microbiome of kidney transplant recipients (KTRs) may reduce infectious complications. The aim of this study is to assess the feasibility of a randomized controlled trial of prebiotics in reducing infections and gastrointestinal symptoms in KTRs.
(design) And Methods: Acute KTRs were recruited to a double-blind, placebo-controlled, randomized trial at a single kidney transplant center.
Background: Despite evidence implicating dietary sodium in the pathogenesis of cardiovascular disease (CVD) in chronic kidney disease (CKD), quality intervention trials in CKD patients are lacking. This study aims to investigate the effect of reducing sodium intake on blood pressure, risk factors for progression of CKD and other cardiovascular risk factors in CKD.
Methods/design: The LowSALT CKD study is a six week randomized-crossover trial assessing the effect of a moderate (180 mmol/day) compared with a low (60 mmol/day) sodium intake on cardiovascular risk factors and risk factors for kidney function decline in mild-moderate CKD (stage III-IV).
Objective: To investigate the effect of dietitian involvement in a multidisciplinary lifestyle intervention comparing risk factor modification for cardiovascular disease with standard posttransplant care in renal transplant recipients (RTR) with abnormal glucose tolerance (AGT).
Design: Randomized controlled trial.
Setting: Hospital outpatient department.