Publications by authors named "Rachael B Cowherd"
Objective: This study aimed to identify patient and provider factors associated with undergoing trial of labor (TOL) among eligible patients with twin gestations.
Study Design: This retrospective cohort study of patients with twin gestations who received care at a large tertiary care center from 2000 to 2016 included individuals with live pregnancies greater than 23 weeks of gestation and cephalic-presenting twin. Patients with a prior uterine scar or contraindication to vaginal delivery were excluded from analyses.
Article Synopsis
- The study aimed to examine how maternal outcomes are influenced by twin chorionicity (the type of placentation) in a large group of obstetric patients from 2000 to 2016.
- Researchers compared outcomes between mothers with monochorionic twins (one placenta) and dichorionic twins (two placentas) by analyzing medical records, excluding certain high-risk cases.
- Results showed no significant differences in gestational diabetes or hypertensive disorders, but monochorionic twin mothers had significantly lower rates of cesarean deliveries.
Adiponectin is a hormone that lowers glucose production by increasing liver insulin sensitivity. Insulin blocks the generation of biochemical intermediates for glucose production by inhibiting autophagy. However, autophagy is stimulated by an essential mediator of adiponectin action, AMPK.
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