Publications by authors named "Rachael A O'Connell"
Purpose: Ocular disease can both alter the retina's oxygen requirements, and decrease its ability to cope with changes in metabolic demand. We examined the influence of a moderate intraocular pressure (IOP) elevation on three outcome measures: arterial and venous oxygen saturation, blood flow, and the pattern electroretinogram (PERG).
Methods: We increased IOP to ˜30 mmHg in 23 healthy participants (22-39 years) using a mechanical probe applied to the eyelid, thereby lowering ocular perfusion pressure (OPP) by ~30%.
Purpose: To determine intrasession and intersession repeatability of retinal vessel oxygen saturation from the Oxymap Retinal Oximeter using a whole image-based analysis technique and so determine optimal analysis parameters to reduce variability.
Methods: Ten fundus oximetry images were acquired through dilated pupils from 18 healthy participants (aged 22 to 38) using the Oxymap Retinal Oximeter T1. A further 10 images were obtained 1 to 2 weeks later from each individual.
Background: To evaluate the effect of phacoemulsification on trabeculectomy function.
Design: Retrospective case-control study.
Participants: Forty-eight patients who underwent trabeculectomy surgery and had at least 2 years of follow up.
Purpose: To use a novel image analysis approach to consider how oxygen saturation changes as a function of vessel width and distance from the nerve and between superior and inferior retinal hemifields.
Methods: Ten images were acquired from one eye of 17 participants (mean [standard deviation] age, 28 [4] years; range, 22-38 years) using the Oxymap T1 retinal oximeter. Every pixel identified by the detection algorithm was extracted, and frequency histograms of retinal vessel oxygen saturation were plotted for each vessel diameter (70-170 μm).