Publications by authors named "Rabia N Yıldız"
Analytical performance evaluation of Sysmex CS-2500 and Stago STA Compact.
Blood Coagul Fibrinolysis
July 2020
Article Synopsis
- The Sysmex Coagulation System-2500 (CS-2500) is an automated analyzer that evaluates coagulation tests like prothrombin time (PT) and activated partial thromboplastin time (aPTT) using optical methods.
- The study compared the CS-2500's performance with the STA-Compact analyzer by examining precision, accuracy, and reference ranges, finding that the CS-2500 had a coefficient of variation of less than 3.5% and less than 9.9% bias in accuracy.
- Although the CS-2500 showed good agreement with the STA-Compact, slight differences were noted, suggesting that future standardization could help harmonize reference ranges across both systems.
Background: Its increasing clinical importance has turned 25-hydroxy-Vitamin D (25(OH)D) into an indispensable test in clinical laboratories. In this study, we aimed to analyze the analytical performances of two widely used immunoassays, namely new restandardized Abbott product Architect 25-OH Vitamin D test and the Beckman Coulter product Access 25(OH) Vitamin D Total Test by making comparisons with the reference method liquid chromatography tandem mass spectrometry (LC-MS/MS).
Methods: The new restandardized Architect I2000SR System (Abbott Laboratories, IL, USA; ref 5P02) and Access2 (Beckman Coulter, Brea, CA, USA; ref B24838) immunoassay were compared with LC-MS/MS (Shimadzu LCMS-8030, Kyoto, Japan) method 25(OH)D test for precision and reproducibility in 90 serum samples.