Publications by authors named "Rabeya Khondaker"
Molecular and functional diversity among synapses is generated, in part, by differential expression of neurotransmitter receptors and their associated protein complexes. -methyl--aspartate receptors (NMDARs) are tetrameric ionotropic glutamate receptors that most often comprise two GluN1 and two GluN2 subunits. NMDARs generate functionally diverse synapses across neuron populations through cell-type-specific expression patterns of GluN2 subunits (GluN2A - 2D), which have vastly different functional properties and distinct downstream signaling.
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- Somatosensory information is transmitted to the cerebral cortex via two pathways involving VPL (ventral posterolateral) for the body and VPM (ventral posteromedial) for the head, each having unique characteristics.
- A study comparing VPL and VPM neurons in mice revealed that VPL neurons are better at firing and adapting rates compared to VPM neurons, which have shorter burst latencies and more intricate dendritic structures.
- The findings suggest significant differences in how VPL and VPM neurons handle excitatory synaptic input and intrinsic firing properties, potentially affecting their roles in processing sensory information and susceptibility to diseases.
Background: COVID-19 caused by SARS-CoV-2 ranges from asymptomatic to severe disease and can cause fatal and devastating outcome in many cases. In this study, we have compared the clinical, biochemical and immunological parameters across the different disease spectrum of COVID-19 in Bangladeshi patients.
Methodology/principal Findings: This longitudinal study was conducted in two COVID-19 hospitals and also around the community in Dhaka city in Bangladesh between November 2020 to March 2021.