Publications by authors named "Rabel R"
Assisted reproduction is one of the significant tools to treat human infertility. Morphological assessment is the primary method to determine sperm and embryo viability during in vitro fertilization cycles. It has the advantage of being a quick, convenient, and inexpensive means of assessment.
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- In 2021, around 80% of the 1.5 million bovine embryos transferred were produced in vitro, but only about 27% led to live births, with 73% experiencing pregnancy failures largely due to poor-quality embryos.
- Current pre-transfer evaluations rely on stereomicroscopy, which often leads to misclassifications of embryo quality.
- Despite many advanced techniques showing promise for better embryo evaluation, most remain impractical due to factors like cost, invasiveness, and complexity, highlighting the need for simpler, more affordable methods in future research.
Lipids play fundamental roles in mammalian embryo preimplantation development and cell fate. Triacylglycerol accumulates in oocytes and blastomeres as lipid droplets, phospholipids influence membrane functional properties, and essential fatty acid metabolism is important for maintaining the stemness of cells cultured in vitro. The growing impact that lipids have in the field of developmental biology makes analytical approaches to analyse structural information of great interest.
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