Development and validation of a nomogram model for predicting the risk of hypertension in Bangladesh.

Background And Objectives: Hypertension (HTN) is a leading cause of non-communicable disease in low- and middle-income countries, including Bangladesh. Thus, the objectives of this study were to investigate the associated risk factors for HTN and develop with validate a monogram model for predicting an individual's risk of HTN in Bangladesh

Materials And Methods: This study exploited the latest nationally representative cross-sectional BDHS, 2017-18 data, which consisted of 6569 participants. LASSO and logistic regression (LR) analysis were performed to reduce dimensionality of data, identify the associated risk factors, and develop a nomogram model for predicting HTN risk in the training cohort.

Dynamic disparities in inorganic nitrogen and phosphorus fluxes into estuarine systems under different flow regimes and streamflow droughts.

Elongated periods of low flow conditions, which can be termed as streamflow droughts, influence the nutrient (e.g., nitrogen and phosphorus) balance in estuarine systems.

Bonactin and Feigrisolide C Inhibit Fungus and Control Wheat Blast Disease.

Wheat blast caused by the (MoT) pathotype is one of the most damaging fungal diseases of wheat. During the screening of novel bioactive secondary metabolites, we observed two marine secondary metabolites, bonactin and feigrisolide C, extracted from the marine bacteria spp. (Act 8970 and ACT 7619), remarkably inhibited the hyphal growth of an MoT isolate BTJP 4 (5) in vitro.

Natural Protein Kinase Inhibitors, Staurosporine, and Chelerythrine Suppress Wheat Blast Disease Caused by .

Protein kinases (PKs), being key regulatory enzymes of a wide range of signaling pathways, are potential targets for antifungal agents. Wheat blast disease, caused by (MoT), is an existential threat to world food security. During the screening process of natural metabolites against MoT fungus, we find that two protein kinase inhibitors, staurosporine and chelerythrine chloride, remarkably inhibit MoT hyphal growth.

Oligomycins inhibit Magnaporthe oryzae Triticum and suppress wheat blast disease.

Oligomycins are macrolide antibiotics, produced by Streptomyces spp. that show antagonistic effects against several microorganisms such as bacteria, fungi, nematodes and the oomycete Plasmopara viticola. Conidiogenesis, germination of conidia and formation of appressoria are determining factors pertaining to pathogenicity and successful diseases cycles of filamentous fungal phytopathogens.