Rare viral infections in children receiving hemopoietic stem cell transplant.

Viral infections are a rare complication in autologous hemopoietic stem cell transplant (HSCT) recipients but represent a frequent cause of disease after allogeneic HSCT. In the last years, there has been an increase in the number of viral diseases observed in these patients. This fact may be at least partially due to an improvement in diagnostic facilities, but the increasing number of transplant procedures and the more severe immunosuppression may also have played an important role.

Cytomegalovirus infection after bone marrow transplantation in children.

Cytomegalovirus (CMV) is a well-known cause of disease occurring after bone marrow transplantation (BMT). The manifestations of CMV range from asymptomatic infection, defined as active CMV replication in the blood in the absence of clinical manifestations or organ failure abnormalities, to CMV disease, characterized by CMV infection with clinical symptoms or organ function abnormalities. Diagnostic procedures to assess the viral load have improved greatly with the increased use of antigenemia, CMV DNA, and immediate early-messenger RNA.

Acyclovir plus CMV immunoglobulin prophylaxis and early therapy with ganciclovir are effective and safe in CMV high-risk renal transplant pediatric recipients.

Cytomegalovirus (CMV) infection is still a major cause of morbidity in high-risk renal transplant recipients. In the present report, we have reviewed our records of renal transplant pediatric recipients (RTPR; mean age 14.1 +/- 4.

Fiberoptic bronchoscopy and bronchoalveolar lavage for the evaluation of pulmonary infiltrates after BMT in children.

Thirty-one fiberoptic bronchoscopies and BAL performed within 4 days after the appearance of pulmonary infiltrates in 28 children who received BMT were reviewed. A causative agent was identified in 67% of patients with diffuse infiltrates (Cytomegalovirus in 8 cases, Pneumocystis carinii in 4) and in 31% of those with localized infiltrates (Aspergillus in 2, bacteria in 2). No relevant side effect was reported.

In-vitro activity of quinolones against different species of staphylococci of recent clinical isolation.

We considered 256 strains of S. aureus (SA) and S. non-aureus (SnA) of recent clinical isolation.

[Evaluation of the fungicidal-fungistatic activity of various preparations for the cure and prevention of seborrheic dermatitis].

Fungistatic and fungicide activity of 4 preparations available on the market for the prevention and treatment of infection due to P. ovale has been defined. P.

[Agglutinating antibodies against Listeria monocytogenes in healthy adult subjects].

The prevalence of antibodies to L. monocytogenes, type 1 and type 4b, in 334 healthy adults of Liguria land was determined by serological agglutination test. Agglutinins at low titer to L.

[Listeria monocytogenes agglutinating antibodies in children].

The AA. relate the results of a serological study on the spreading of listeria infection over the pediatric population of Liguria. The research of agglutinating antibodies for types 1 and 4b of L.

[Status of tetanus immunity in a group of children in Liguria].

By means of the passive hemagglutination test the antitetanus immunity in a group of 380 children, aged between 0 and 14 years, of various Italian regions, was ascertained. On the whole, 62.9% of the subjects showed a titer equal to, or higher than 1024, equivalent to 0.

[Serological studies of the diffusion of toxoplasmosis in a sample of the population of northern Italy].

The prevalence of toxoplasmosis as results by serologic tests (agglutination test = Fulton test and indirect emoagglutination test) of 904 subjects of North Italy was determined. Serologic signs of toxoplasmosis were present by only one or by both two tests in 66.4% and respectively in 64.

[Staphylococci in children's pathology (author's transl)].

In this paper we report and make short comments on data concerning 237 strains of Staphylococci isolated from 8820 samples of various pathologic material we tested when normal working in the Laboratory of our pediatric Institute. We noticed that 34.1% of cases were St.

[Results and consideration on blood cultures activity in a great children Hospital (author's transl)].

This paper reports the results of blood cultures of a great children Hospital during the last three years. It regards 2164 blood cultures, 140 of which positive, and analyses the reasons that probably determinate the detected deficencies and defects.