Forearm Nonunion: Characterization and Management.

Adult forearm nonunion should be investigated prior to developing a treatment strategy: "Why did the fracture not heal?" Optimizing the patient's biology and the stability at the nonunion site are critical for a successful outcome. This review concisely discusses the initial work-up, including history, physical examination, imaging, and laboratory testing, as well as available surgical techniques-irrigation and debridement with deep cultures, revision open reduction internal fixation with or without biological adjuvant therapies, cancellous autograft, tricortical iliac crest, reamer/irrigator/aspirator, allograft, vascularized free-fibula and induced-membrane technique.

Acamprosate rescues neuronal defects in the Drosophila model of Fragile X Syndrome.

Aims: Several off-label studies have shown that acamprosate can provide some clinical benefits in youth with Fragile X Syndrome (FXS), an autism spectrum disorder caused by loss of function of the highly conserved FMR1 gene. This study investigated the ability of acamprosate to rescue cellular, molecular and behavioral defects in the Drosophila model of FXS.

Main Methods: A high (100μM) and low (10μM) dose of acamprosate was fed to Drosophila FXS (dfmr1 null) or genetic control (w) larvae and then analyzed in multiple paradigms.

Calculations of two-dimensional electric field and potential distributions around electrodes in conducting media.

Tumor cells can be killed by heating to 42.5 degrees C. It is convenient to localize heating by passing electric current at 500 kHz through tissue between a pair of electrodes.

Calculations of two-dimensional electric field and potential distributions aroun electrodes in conducting media.

Tumor cells can be killed by heating to 42.5degreesC. It is convenient to localize heating by passing electric current at 500 kHz through tissue between a pair of electrodes.

Tissue chemical analysis with muonic x rays.

The stopped muon channel at the Clinton P. Anderson Meson Physics Facility was used as a source of muons for studying the elemental composition of tissue via muonic x rays. The x-ray spectra from several types of tissue were used to determine the amounts of carbon, nitrogen, and oxygen present.