Objective: Obesity is a global public health challenge and strongly associated with type 2 diabetes (T2D), but its burden and effects are not well understood in people with type 1 diabetes (T1D). Particularly, the link between obesity and chronic kidney disease (CKD) in T1D is poorly characterized.
Research Design And Methods: We included all T1D and, for comparison, T2D in the Geisinger Health System from 2004 to 2018.
A 26-year-old man presented with a 4-week history of right lower quadrant abdominal pain which was managed conservatively at home with ibuprofen. Three days later, he presented to the emergency department with worsening pain and swelling following an episode of coughing and slipping in the bathroom. Following his admission, CT angiography showed an active bleed into a 4.
View Article and Find Full Text PDFDistal radius fractures are one of the most common orthopedic injuries, particularly in the elderly population. Distal radius nonunions are rare and are usually associated with a patient's underlying health conditions. We present a patient who developed a distal radius nonunion following treatment of an open wrist fracture with an external fixation frame.
View Article and Find Full Text PDFTo determine the efficacy and safety of a diabetic ketoacidosis (DKA)-Power Plan (PP) for guiding intravenous (IV) insulin infusions prior to anion gap (AG) closure and administering subcutaneous (SC) insulin ≥1 hour before discontinuing IV insulin. Retrospective chart review of patients with DKA before (pre-PP) (n = 60) and following (post-PP) (n = 60) implementation of a DKA-PP. Groups were compared for percentage of patients for whom IV insulin therapy was continued until AG closure, the percentage of patients receiving SC insulin ≥1 hour before discontinuation of IV insulin, and percentage of patients with rebound DKA during the index hospitalization.
View Article and Find Full Text PDFThe 7th annual Health Information Technology (IT) issue provides a window into how health IT tools are working well, how they may not be working as intended, and what we can do to continue making progress toward optimal use of technology to accomplish our shared goals: better health, better care experience, and lower per capita cost.
View Article and Find Full Text PDFIn order to address gaps in the literature surrounding the acquisition of translation equivalents (TEs) in young bilinguals, two experiments were conducted. In Experiment 1, TEs were measured in the expressive vocabularies of thirty-four French-English bilinguals at 1;4, 1;10, and 2;6 using the MacArthur Bates CDI. Children's acquisition of TEs occurred gradually, with more balanced ratios of exposure and vocabulary associated with larger proportions of TEs at each wave.
View Article and Find Full Text PDFObjective: The number of people with diabetes using continuous subcutaneous insulin infusions (CSII) with an insulin pump has risen dramatically, creating new challenges when these patients are admitted to the hospital for surgical or other procedures. There is limited literature guiding CSII use during surgical procedures.
Methods: The study was carried out in a large, urban, tertiary care hospital.
Pol Arch Med Wewn
December 2009
Substantial observational data has linked hyperglycemia in hospitalized patients with poor patient outcomes. While early studies suggested improved clinical outcomes with interventions targeting near euglycemia, more recent studies have yielded inconsistent results, with the suggestion of harm with more severe hypoglycemia. The American Association of Clinical Endocrinologists and American Diabetes Association published a revised consensus statement on inpatient glycemic management that takes into account this recent evidence.
View Article and Find Full Text PDFAm J Physiol Regul Integr Comp Physiol
January 2006
Increased activity of proinflammatory/stress pathways has been implicated in the pathogenesis of insulin resistance in obesity. However, the effects of obesity on the activity of these pathways in skeletal muscle, the major insulin-sensitive tissue by mass, are poorly understood. Furthermore, the mechanisms that activate proinflammatory/stress pathways in obesity are unknown.
View Article and Find Full Text PDFCritical care nurses know that some families handle the anxiety of the critical illness well and can continue to learn and problem-solve, while others seem to be overwhelmed with the anxiety and are unable to function. The way families handle the anxiety are important to their ability to learn. With shorter stays, the nurse needs to help families to handle their anxiety, so they can prepare for the patient's ultimate discharge home.
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