Publications by authors named "R de la Garza"
Background And Objectives: Immediate lymphatic reconstruction (ILR) performed to prevent breast cancer related lymphedema is not consistently covered by insurance payors in the United States.
Methods: Retrospective review was performed on a prospective database of ILR candidates from 2018 to 2022. Candidates were identified as patients with clinical axillary lymph node involvement at the time of breast cancer diagnosis.
Article Synopsis
- Photoluminescence (PL) spectroscopy is a highly sensitive and quick method for detecting molecules, and zinc oxide (ZnO) shows promising optical properties, especially when combined with graphene quantum dots (GQD) for applications in photocatalysis and sensing.* -
- The study examined the PL performance of ZnO and ZnO-GQD nanocomposites in both solid and aqueous phases, identifying six distinctive peaks in their emissions and emphasizing the key role of the peak at around 415 nm where GQD interacts with ZnO.* -
- Varying GQD concentrations affected PL emission in the aqueous phase, with low concentrations weakening the ZnO-GQD contact, high concentrations enhancing it, and medium concentrations maintaining
Glioblastoma presents a formidable clinical challenge because of its complex microenvironment. Here, we characterized tumor-associated foam cells (TAFs), a type of lipid droplet-loaded macrophage, in human glioblastoma. Through extensive analyses of patient tumors, together with in vitro and in vivo investigations, we found that TAFs exhibit distinct protumorigenic characteristics related to hypoxia, mesenchymal transition, angiogenesis, and impaired phagocytosis, and their presence correlates with worse outcomes for patients with glioma.
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- The study examines the use of antegrade continence enemas (ACE) in children with medically refractory fecal incontinence and constipation, focusing on patient perceptions and the potential to discontinue the use of the associated appendicostomy/cecostomy tube.
- Data was gathered from 165 patients who underwent ACE procedures between 2012 and 2021, with 82 completing a follow-up survey revealing satisfaction rates and reasons for discontinuing flushes.
- Findings indicate a high satisfaction rate (76.8% very satisfied), with 21.8% of patients able to stop using flushes for various reasons, and a strong recommendation rate for ACE among respondents.
The human silencing hub (HUSH) complex binds to transcripts of LINE-1 retrotransposons (L1s) and other genomic repeats, recruiting MORC2 and other effectors to remodel chromatin. How HUSH and MORC2 operate alongside DNA methylation, a central epigenetic regulator of repeat transcription, remains largely unknown. Here we interrogate this relationship in human neural progenitor cells (hNPCs), a somatic model of brain development that tolerates removal of DNA methyltransferase DNMT1.
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