Publications by authors named "R de la Faille"

Background: Catheter-related bloodstream infections (CRBIs) remain a major cause of mortality in haemodialysis (HD) patients with central venous catheters (CVCs), especially because of the non-specific symptomatology and the delay in microbiological diagnosis with possible use of non-optimal empiric antibiotics. Moreover, empiric broad-spectrum antibiotics increase antibiotic resistance development. This study aims to evaluate the diagnostic performance of real-time polymerase chain reaction (rt-PCR) in suspected HD CRBIs compared with blood cultures.

View Article and Find Full Text PDF
Article Synopsis
  • The study evaluates different methods for measuring plasma albumin in hemodialysis patients to accurately diagnose malnutrition.
  • It highlights significant variations in albumin levels based on the testing method, with existing thresholds for hypoalbuminemia leading to misclassifications.
  • The authors suggest adjusting hypoalbuminemia cut-off values for two methods (bromocresol purple and immunoturbidimetry) to improve diagnostic accuracy in identifying malnutrition among these patients.
View Article and Find Full Text PDF

Patients in hemodialysis on central venous catheter as vascular access are at risk of infections. Catheter-related bloodstream infection is one of the most serious catheter-complications in hemodialysis patients. Its clinical and microbiological diagnosis is challenging.

View Article and Find Full Text PDF

Introduction: Although living kidney donation is not a high-risk surgery, there is still a need to identify situations at risk of kidney disease after uninephrectomy. Estrogens exhibit a protective role against various nephropathies. The aim of this study was to assess renal adaptation following nephrectomy according to menopausal status in women.

View Article and Find Full Text PDF

Background: Gitelman syndrome is a salt-losing tubulopathy caused by mutations in the gene, which encodes the thiazide-sensitive sodium-chloride cotransporter. Previous studies suggested an intermediate phenotype for heterozygous carriers.

Methods: To evaluate the phenotype of heterozygous carriers of pathogenic mutations, we performed a cross-sectional study of patients with Gitelman syndrome, heterozygous carriers, and healthy noncarriers.

View Article and Find Full Text PDF