Publications by authors named "R de Franchis"

Article Synopsis
  • * The International Multicenter Pediatric Portal Hypertension Registry (IMPPHR) was created to gather data on pediatric mortality from variceal hemorrhage and strategies for prevention.
  • * IMPPHR was initiated following discussions at pediatric portal hypertension meetings, began in 2020, and aims to collect data from over 700 subjects across 44 centers until data closure in 2024.
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Article Synopsis
  • The Italian Ministry of Health implemented a COVID vaccination plan for frail patients and healthcare workers starting in January 2021, using a three-dose regimen.
  • A study involving 53 family pediatricians was conducted to assess immune responses post-vaccination through various laboratory techniques, revealing that while antibody levels rose significantly after the third dose, they did not predict infection risk.
  • The research found that after the booster, activated T cell responses, particularly CD8 IFN-γ levels, were significantly associated with a lower risk of infection in the following six months, highlighting potential implications for other vaccine strategies.
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Background: Enteroscopy plays an important role in the management of small bowel bleeding. However, current guidelines are not specifically designed for small bowel bleeding and recommendations from different international societies do not always align. Consequently, there is heterogeneity in the definitions of clinical entities, clinical practice policies, and adherence to guidelines among clinicians.

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