Publications by authors named "R Zalacain"
Improved phenotyping in pneumonia is necessary to strengthen risk assessment. Via a feasible and multidimensional approach with basic parameters, we aimed to evaluate the effect of host response at admission on severity stratification in COVID-19 and community-acquired pneumonia (CAP). Three COVID-19 and one CAP multicenter cohorts including hospitalized patients were recruited.
View Article and Find Full Text PDFIs the long-term mortality similar in COVID-19 and community-acquired pneumonia?
Front Med (Lausanne)
October 2023
Article Synopsis
- The study investigates the long-term mortality rates associated with COVID-19 and community-acquired pneumonia (CAP) in patients who were hospitalized and later discharged.
- It utilizes a retrospective analysis of two cohorts, applying Bayesian logistic regression to control for confounding factors while assessing mortality outcomes after one year.
- Findings suggest that both types of pneumonia have comparable long-term mortality rates, with no significant difference after adjustments, indicating a low probability of distinguishing between them based on mortality risk.
Introduction And Objectives: High-flow nasal cannula oxygen therapy (HFNC) has been successfully used for the treatment of acute hypoxaemic respiratory failure (AHRF) secondary to SARS-CoV-2 pneumonia and being effective in reducing progression to invasive mechanical ventilation. The objective of this study was to assess the usefulness of HFNC on a hospital ward for the treatment of AHRF secondary to SARS-CoV-2 pneumonia and its impact on the need for intensive care unit (ICU) admission and endotracheal intubation. Other objectives include identifying potential physiological parameters and/or biomarkers for predicting treatment failure and assessing the clinical course and survival.
View Article and Find Full Text PDFImpact of outdoor air pollution on severity and mortality in COVID-19 pneumonia.
Sci Total Environ
October 2023
The relationship between exposure to air pollution and the severity of coronavirus disease 2019 (COVID-19) pneumonia and other outcomes is poorly understood. Beyond age and comorbidity, risk factors for adverse outcomes including death have been poorly studied. The main objective of our study was to examine the relationship between exposure to outdoor air pollution and the risk of death in patients with COVID-19 pneumonia using individual-level data.
View Article and Find Full Text PDFObjectives: To analyze the differences in short- and long-term prognosis and the predictors of survival between patients with community-acquired Legionella and Streptococcus pneumoniae pneumonia, diagnosed early by urinary antigen testing (UAT).
Methods: Prospective multicenter study conducted in immunocompetent patients hospitalized with community-acquired Legionella or pneumococcal pneumonia (L-CAP or P-CAP) between 2002-2020. All cases were diagnosed based on positive UAT.