Flexible Piezoresistive Film Pressure Sensor Based on Double-Sided Microstructure Sensing Layer.

Flexible thin-film pressure sensors have garnered significant attention due to their applications in industrial inspection and human-computer interactions. However, due to their ultra-thin structure, these sensors often exhibit lower performance, including a narrow pressure response range and low sensitivity, which constrains their further application. The most commonly used microstructure fabrication methods are challenging to apply to ultra-thin functional layers and may compromise the structural stability of the sensors.

Dual Roles of Heterotrophic Ammonia-Oxidizing Bacteria in Enhancing Compensatory Growth upon Post-Drought in Maize.

This study investigates the mechanisms driving maize compensatory growth upon post-drought, to reveal how the root's original cytokinins are regulated by the two-fold roles of heterotrophic bacteria with ammonia-oxidizing (HAOB) capabilities. The HAOB' dual roles encompass influencing root cytokinin synthesis and transport through nitrification and a direct pathway. Experiment 1 involved introducing the application of varying amounts of NO to the roots to examine how nitrification affects cytokinin roots-to-leaves transport.

Mural Cells Initiate Endothelial-to-Mesenchymal Transition in Adjacent Endothelial Cells in Extracranial AVMs.

Extracranial arteriovenous malformations (eAVMs) are complex vascular lesions characterized by anomalous arteriovenous connections, vascular instability, and disruptions in endothelial cell (EC)-to-mural cell (MC) interactions. This study sought to determine whether eAVM-MCs could induce endothelial-to-mesenchymal transition (EndMT), a process known to disrupt vascular integrity, in the eAVM microenvironment. eAVM and paired control tissues were analyzed using RT-PCR for EC (, , and ) and EndMT-specific markers (, , , /.

Neonatal systemic gene therapy restores cardiorespiratory function in a rat model of Pompe disease.

Absence of functional acid-α-glucosidase (GAA) leads to early-onset Pompe disease with cardiorespiratory and neuromuscular failure. A novel Pompe rat model ( ) was used to test the hypothesis that neonatal gene therapy with adeno-associated virus serotype 9 (AAV9) restores cardiorespiratory neuromuscular function across the lifespan. Temporal vein administration of AAV9-DES-GAA or sham (saline) injection was done on post-natal day 1; rats were studied at 6-12 months old.

Recent Advances in Two-Dimensional Ferromagnetic Materials-Based van der Waals Heterostructures.

Two-dimensional (2D) ferromagnetic materials are subjects of intense research owing to their intriguing physicochemical properties, which hold great potential for fundamental research and spintronic applications. Specifically, 2D van der Waals (vdW) ferromagnetic materials retain both structural integrity and chemical stability even at the monolayer level. Moreover, due to their atomic thickness, these materials can be easily manipulated by stacking them with other 2D vdW ferroic and nonferroic materials, enabling precise control over their physical properties and expanding their functional applications.