Three-dimensional turbo-spin-echo amide proton transfer-weighted and intravoxel incoherent motion imaging mri for triple-negative breast cancer: a comparison with molecular subtypes and histological grades.

Objective: To investigate associations between breast cancer molecular subtype and intravoxel incoherent motion imaging (IVIM) and amide proton transfer-weighted (APTw).

Methods: This prospective study involved 264 patients with suspected breast tumors who underwent both breast APTw and IVIM MRI. The maximum diameter of the tumor (Dmax), APT value, apparent diffusion coefficient (ADC), diffusion coefficient (D), pseudo diffusion coefficient (D*), and perfusion fraction (f) values along with histological subtype, grade, and prognostic factors (Ki-67, estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor-2 (HER-2), were compared.

Real needs of end-stage kidney disease patients awaiting kidney transplantation in China: A qualitative study.

Objective: To explore the true needs of patients awaiting kidney transplantation in China through the language used by them. We addressed the literature gap concerning this critical aspect of patient care and counselling.

Methods: We interviewed 32 individuals-22 who were on the waiting list for a kidney transplant and 10 were kidney transplant recipients.

Contrasting kinetics of arsenic release from As-bearing ferrihydrite coprecipitates by distinct sulfate-reducing bacteria.

Microbial sulfate reduction plays key roles in arsenic (As) biotransformation and release in groundwater aquifers; however, influences by distinct sulfate-reducing strains on the transformation of As-bearing iron (oxyhydr)oxide under different sulfate availability and associated As mobilization are not clear. In this study, anaerobic batch experiments were conducted to clarify the transformation processes of As-bearing ferrihydrite mediated by two distinct sulfate-reducing strains. Results showed that both the purchased model strain Desulfovibrio vulgaris (D-1) and the Citrobacter sp.

EXO1's pan-cancer roles: diagnostic, prognostic, and immunological analyses through bioinformatics.

Cancer remains a leading cause of mortality worldwide, with human exonuclease 1 (EXO1) emerging as a key player in DNA repair and damage response pathways, critical for genomic stability and tumor evolution. The aim of this study was to conduct a comprehensive pan-cancer analysis to elucidate the multifaceted roles of EXO1 in various malignancies. Leveraging public databases including TCGA, GTEx, HPA, cBioPortal, UALCAN, STRING, CancerSEA and TISIDB database, we examined EXO1's expression, diagnostic potential, prognostic significance, mutational characteristics, functional roles, and immunological effects across different cancer types.

Effect of acupuncture in patients with postprandial distress syndrome: study protocol for a randomized controlled trial.

Background: Postprandial distress syndrome (PDS) is the prominent subtype in patients with functional dyspepsia (FD) and currently lacks a satisfactory treatment. Acupuncture has become a promising alternative and complementary therapy for managing FD. However, high-level clinical evidence supporting the use of acupuncture for FD is limited.