Publications by authors named "R Willoughby"

The transition of Freud's into its first English language incarnation as , translated by A.A. Brill, took several years to effect, the process being beset with conceptual, practical, legal, and political obstacles.

View Article and Find Full Text PDF

Background: Severe COVID-19 is uncommon, restricted to 19% of the total population. In response to the first virus wave (alpha variant of SARS-CoV-2), we investigated whether a biomarker indicated severity of disease and, in particular, if variable expression of angiotensin converting enzyme 2 (ACE2) in blood might clarify this difference in risk and of post COVID -19 conditions (PCC).

Methods: The IRB-approved study compared patients hospitalized with severe COVID-19 to healthy controls.

View Article and Find Full Text PDF

Background: Rabies is a highly fatal disease. Once symptoms develop, death usually occurs within days. Survivors were occasionally reported in the literatures.

View Article and Find Full Text PDF
Article Synopsis
  • Cardiac fibrosis is a concerning complication for survivors of SARS-CoV-2 infections, potentially leading to heart rhythm issues.
  • Researchers studied human heart tissue to assess levels of HSP47, a protein linked to collagen production, and found higher amounts of HSP47 and collagen in about 40% of the COVID-19 patients, suggesting a "profibrotic phenotype."
  • The study highlights the connection between certain immune cells, myofibroblasts, and collagen deposition, indicating a need for further research on how COVID-19 contributes to heart damage.
View Article and Find Full Text PDF