Publications by authors named "R Whiteley"

Purpose: To compare patient-reported outcomes between acute ligamentous ankle injuries 1) without anterior syndesmosis involvement and 2) with anterior syndesmosis involvement (without clinical instability).

Study Design: Prospective cohort study.

Methods: Between September 2016 and December 2020 all athletes (≥18) with an acute ankle injury presenting within 7 days post-injury were screened for eligibility.

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Article Synopsis
  • The study aimed to establish the Fragility Index for hamstring injury risk factors, which indicates how many participants would need to change risk classification for a statistically significant risk factor to become nonsignificant.
  • Researchers conducted a retrospective analysis of 78 articles focused on hamstring injury risk factors, creating 2 × 2 contingency tables to analyze relative risk and confidence intervals.
  • Findings showed that the median Fragility Index for both modifiable and nonmodifiable risk factors was 3, with over 35% of these factors having a Fragility Index of 2 or less, highlighting that many significant associations are fragile and should be interpreted with caution.
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Article Synopsis
  • The study aimed to analyze and categorize the circumstances surrounding sudden-onset hamstring injuries in professional football players using video footage from matches.
  • Researchers reviewed injuries from the Qatar Stars League, focusing on players aged 18 and older, and found that running was the most significant factor, accounting for 86% of the injuries.
  • Results revealed that injuries frequently occurred during short sprints (0-10 m) and were often linked to player contact and balance issues, emphasizing the role of pressing actions in a significant percentage of cases.
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Objectives: Neuronal ceroid lipofuscinosis type 2 (CLN2-disease) is an inherited childhood-onset neurodegenerative condition, with classical early features of speech delay, epilepsy, myoclonus, ataxia, and motor regression. This study aimed to better characterize the spectrum of movement disorders in CLN2-disease in a cohort of children receiving enzyme replacement therapy (ERT).

Methods: A cohort of 18 children attending a single center for treatment with cerliponase alfa ERT was systematically assessed using a standardized structured history and a double-scored, video-recorded examination using the Unified Batten Disease Rating Scale (UBDRS) and Abnormal Involuntary Movement Scale.

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Objectives: Studies identifying clinical and MRI reinjury risk factors are limited by relatively small sample sizes. This study aimed to examine the association between baseline clinical and MRI findings with the incidence of hamstring reinjuries using a large multicentre dataset.

Methods: We merged data from four prospective studies (three randomised controlled trials and one ongoing prospective case series) from Qatar and the Netherlands.

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