Publications by authors named "R Whitehill"
Article Synopsis
- - The study examined the occurrence of thromboembolic complications in young patients (under 25) with atrial fibrillation (AFib) or atrial flutter (AFl) and analyzed how anticoagulation is practiced in this group across multiple medical centers from 2000 to 2019.
- - Among 210 patients with 311 episodes of AFib/AFl, 12 episodes were linked to blood clots, predominantly in patients with structural heart disease, while only 34% were discharged on aspirin and 27% on anticoagulants.
- - The findings indicate that while thromboembolic events can occur in this age group, they are generally rare after treatment like cardioversion, and the CH
Background: Calmodulinopathies are rare inherited arrhythmia syndromes caused by dominant heterozygous variants in , , or , which each encode the identical CaM (calmodulin) protein. We hypothesized that antisense oligonucleotide (ASO)-mediated depletion of an affected calmodulin gene would ameliorate disease manifestations, whereas the other 2 calmodulin genes would preserve CaM level and function.
Methods: We tested this hypothesis using human induced pluripotent stem cell-derived cardiomyocyte and mouse models of pathogenic variants.
Background: Infants with complete heart block (CHB) require epicardial pacemaker (PM) insertion. Prior studies described epicardial pacing outcomes in infants and children, although they were limited by small or heterogeneous populations.
Objective: This study aimed to explore patient- and procedure-level associations with device complications in infants with CHB who received a permanent PM.
Objective: Children with prolonged hospital admissions for CHD often develop delirium. Antipsychotic medications (APMs) have been used to treat delirium but are known to prolong the QTc duration. There is concern for prolongation of the QTc interval in cardiac patients who may be more vulnerable to electrocardiogram (ECG) changes and may have postoperative QTc prolongation already.
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