Publications by authors named "R Whaley"
Article Synopsis
- High-grade follicular cell-derived non-anaplastic thyroid carcinomas are rare tumors, particularly in patients under 21, and are more commonly diagnosed in older adults.
- A study focused on 15 patients aged 9-20 revealed various classifications of thyroid carcinoma, including poorly differentiated and differentiated high-grade types, with specific genetic alterations noted, especially in the DICER1 and TP53 genes.
- Immunohistochemistry tests indicated the presence of BRAF V600E mutations and PTEN alterations, highlighting the molecular complexity of these thyroid cancers in younger populations.
Introduction: This study applied a novel tobacco regulatory science paradigm to characterize inter-product variation in the appeal and sensory features of emerging commercial and therapeutic oral nicotine products (ONPs) among young adults that vape e-cigarettes.
Methods: Twenty-three young adults without ONP experience who use e-cigarettes completed a single-blind, single-visit remote lab study. Participants rated appeal and sensory characteristics during 5-minute standardized self-administrations of 8 ONPs (4 fruit, 4 mint) from various brands (Lucy, Rouge, Solace, Nicorette, On!, Velo).
The FGFR3::TACC3 fusion has been reported in subsets of diverse cancers including urothelial and squamous cell carcinomas (SCC). However, the morphology of FGFR3::TACC3-positive head and neck carcinomas has not been well studied and it is unclear if this fusion represents a random event, or if it might characterize a morphologically distinct tumor type. We describe nine FGFR3::TACC3 fusion-positive head and neck carcinomas affecting six males and three females aged 38 to 89 years (median, 59).
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