Glucose homeostasis in rats exposed to magnetic fields.

The development of diagnostic and therapeutic applications of magnetic fields, especially with regard to magnetic resonance imaging (MRI), draws attention to accompanying possible adverse effects. Recent investigations revealing an increase in insulin release in diabetic rats, increase in glycogen, and decrease in glucose level in rats exposed to magnetic fields, have provided the stimulus for the current studies. Rats were exposed to uniform constant magnetic fields of 10(-3) T and 10(-2) T, 1 hour each day, for a period of ten days.

Structural and functional changes in organelles of liver cells in rats exposed to magnetic fields.

Exposure of rats to magnetic fields of 10(-3) and 10(-2) T for 1 hr daily generated structural changes in hepatocytes mitochondria, endoplasmic reticulum, and ribosomes. Simultaneously there was an increase in the activities of the mitochrondrial respiratory enzymes: NADH dehydrogenase, succinic dehydrogenase, and cytochrome oxidase. The extent of the changes in liver cell properties following exposure depend on the duration of exposure to and the strength of the applied magnetic fields.

Effect of static magnetic field on some enzymes activities in rats.

The magnetic field of 0.008 T and 0.15 T inductions influence lasting 7 weeks (7 days a week), 1 h daily determines the increase of the activity of cytoplasmatic enzymes (glutamic pyruvic transaminase, glutamic oxalacetic transaminase, lactic dehydrogenase), the decrease of cholinesterase activity and the growth of alkaline phosphatase activity in the plasma of the examined animals.

Effect of chronic exposure to static magnetic field upon the serum glutamic pyruvic transaminase activity GPT and morphology of the cardiac muscle, skeletal muscles, kidneys, cerebellum and lung tissue in guinea pigs.

In a cycle of investigations concerning the pathogenesis of functional changes caused by the influence of magnetic field of induction occurring in laboratory and industrial conditions glutamic pyruvic transaminase activity in external blood and morphological picture of cardiac muscle, skeletal muscles, kidneys, cerebellum and lung tissue in guinea pigs were examined. Static homogeneous magnetic field as low as 0.005 T produced a statistically significant decrease in GPT activity.