Publications by authors named "R W Skelton"

Article Synopsis
  • - Preclinical studies show that human pluripotent stem cell-derived cardiomyocytes (PSC-CMs) can help repair injured hearts, with multiple clinical trials underway.
  • - Ventricular arrhythmias (EAs) can occur after injecting PSC-CMs into the heart, linked to cellular diversity within the transplanted cells, particularly arrhythmogenic subpopulations like atrial and pacemaker-like cardiomyocytes.
  • - Identifying specific surface markers may help differentiate risky PSC-CMs from safer ones, and both drug treatments and other interventions can help manage or eliminate these arrhythmias in the experimental model used.
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The Editorial Office retracts the article, "Contribution of Host Immune Responses Against Influenza D Virus Infection Toward Secondary Bacterial Infection in a Mouse Model" [...

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The African Restionaceae (Poales), the dominant graminoid layer in the megadiverse Cape Floristic Region of South Africa, are distributed across a wide range of moisture availability, yet currently there is very little known about the underlying hydraulics of this group. We tested two methods for measuring culm vulnerability to embolism, the optical and pneumatic methods, in three species of Cannomois ranging in habitat from semi-riparian (Cannomois virgata) to dryland (Cannomois parviflora and C. congesta).

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Doxorubicin is a commonly used anti-cancer drug used in treating a variety of malignancies. However, a major adverse effect is cardiotoxicity, which is dose dependent and can be either acute or chronic. Doxorubicin causes injury by DNA damage, the formation of free reactive oxygen radicals and induction of apoptosis.

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