Phase 1 Study of Adjuvant Allogeneic Granulocyte-Macrophage Colony-Stimulating Factor-Transduced Pancreatic Tumor Cell Vaccine, Low-Dose Cyclophosphamide, and Stereotactic Body Radiation Therapy Followed by FOLFIRINOX in High-Risk Resected Pancreatic Ductal Adenocarcinoma.

Purpose: Local and distant progression remains common following resection of resectable pancreatic ductal adenocarcinoma (PDAC) despite adjuvant multiagent chemotherapy. We report a prospective institutional phase 1 trial incorporating adjuvant GVAX vaccine, low-dose cyclophosphamide (Cy), and stereotactic body radiation therapy (SBRT) followed by FOLFIRINOX (FFX) among patients who underwent resection of high-risk PDAC.

Patients And Methods: The study design was a modified 3+3.

Future Shorelines: A Living Shoreline Site Selection and Design Decision Support Tool that Incorporates Future Conditions Induced by Sea Level Rise.

Most living shoreline site selection and design decision support tools are based upon existing environmental conditions. We developed a web-based, geospatial tool called Future Shorelines that integrates high-resolution landscape elevation data and a matrix of locally derived NOAA Interagency Sea Level Rise Scenarios to characterize future conditions of submergence and shoreline translation induced by sea level rise. Once the practitioner selects a location of interest, sea level rise scenario (e.

Subtle or Covert Abuse Within Intimate Partner Relationships: A Scoping Review.

Intimate partner violence (IPV) is a global health problem enacted with varying degrees of severity, leading to mental and physical damage. Despite the acknowledgment that perpetration can be enacted in a subtle or covert way, there is a paucity of literature defining and describing such subtle abuse. Consequently, understanding about the behaviors and impacts of subtle abuse is limited, and there is a potential inability by therapists to recognize it in their clients.

Nursing students' knowledge of working with D/deaf and hard of hearing patients: Evaluation of a deaf awareness elearning package.

Aim: The aim of this study was to evaluate a newly developed Deaf awareness e-learning package with nursing students at one university in Wales, UK.

Background: D/deaf and hard of hearing communities face a multitude of barriers when accessing and receiving healthcare leading to under diagnosis of health conditions and poorer health outcomes in general. Lack of awareness, teaching, and exposure to the D/deaf and hard of hearing populations during health care professional training programmes has been shown to contribute to this health disparity.

Wohlfahrtiimonas chitiniclastica Bacteremia: A Rare Case of a Male With Maggot-Infested Lower Extremity Wounds.

 () is an emerging gram-negative bacillus rarely found in patients presenting with fly myiasis or parasitic larvae infection. Here, we present the case of a 58-year-old male who presented with bacteremia from lower extremity wounds complicated by fly larvae infestation. Blood cultures were analyzed with matrix-assisted laser desorption ionization-time of flight mass spectrometry, which identified .