Publications by authors named "R W Noda"

To mitigate global warming, replacing concrete and steel with timber as the primary construction material for construction projects, such as check dams, is being promoted in Japan and other countries. Timber check dams have more limited installation sites than concrete or steel dams because of installation conditions such as locations less susceptible to debris flows and locations where there is constant running water. However, even when the installation conditions are met, engineers and contractors are reluctant to select timber as a construction material because of its high construction cost.

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Exacerbation of scarring can originate from a minority fibroblast population that has undergone inflammatory-mediated genetic changes within the wound microenvironment. The fundamental relationship between molecular and spatial organization of the repair process at the single-cell level remains unclear. We have developed a novel, high-resolution spatial multiomics method that integrates spatial transcriptomics with scRNA-Seq; we identified new characteristic features of cell-cell communication and signaling during the repair process.

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  • Minimal change disease (MCD) is a leading cause of nephrotic syndrome, making early and accurate diagnosis crucial, yet it typically requires a kidney biopsy for confirmation.
  • This study explores the use of machine learning algorithms to create non-invasive models for diagnosing MCD by analyzing data from 248 patients with nephrotic syndrome.
  • Among the algorithms tested, TabPFN performed the best, achieving high accuracy metrics and identifying key predictors like C3, total cholesterol, and urine red blood cells, suggesting that machine learning could effectively aid in MCD diagnosis.
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  • A 66-year-old man had a type of brain tumor called a meningioma that was monitored for 13 years.
  • Over time, the tumor shrank significantly without treatment.
  • This case shows that sometimes tumors can get smaller on their own, and it's important to consider non-surgical options for older patients or those with other health issues.
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  • Recent advancements in radiological imaging allow for the detection of micro-remnant arteriovenous malformations (AVMs) after gamma knife radiosurgery (GKS), which were previously undetectable.
  • This study analyzed patients at NTT Medical Center Tokyo who underwent both 2D digital subtraction angiography and 3D rotational angiography as follow-up after GKS, aiming to identify undetected micro-remnants.
  • Results showed that 3D-RA successfully detected micro-remnants in all cases, suggesting its effectiveness in treatment planning and potential enhancement of GKS retreatment outcomes.
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