To mitigate global warming, replacing concrete and steel with timber as the primary construction material for construction projects, such as check dams, is being promoted in Japan and other countries. Timber check dams have more limited installation sites than concrete or steel dams because of installation conditions such as locations less susceptible to debris flows and locations where there is constant running water. However, even when the installation conditions are met, engineers and contractors are reluctant to select timber as a construction material because of its high construction cost.
View Article and Find Full Text PDFExacerbation of scarring can originate from a minority fibroblast population that has undergone inflammatory-mediated genetic changes within the wound microenvironment. The fundamental relationship between molecular and spatial organization of the repair process at the single-cell level remains unclear. We have developed a novel, high-resolution spatial multiomics method that integrates spatial transcriptomics with scRNA-Seq; we identified new characteristic features of cell-cell communication and signaling during the repair process.
View Article and Find Full Text PDFJ Neurosurg Case Lessons
October 2024