Publications by authors named "R W Lacey"

Objectives: Sandwich carers provide care to ageing parents or older relatives while simultaneously raising dependent children. There has been little focus on how mental and physical health trajectories change around becoming a sandwich carer - a gap this study aims to fill.

Study Design: Prospective longitudinal study.

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Article Synopsis
  • - The study explored the relationship between adverse childhood experiences (ACEs) and mental health issues, noting that supportive adult relationships can help mitigate these problems.
  • - Using a twin-difference design, researchers analyzed data from a UK twin study to determine whether the protective effects of maternal warmth and adult support on mental health were truly causal, controlling for genetic and environmental factors.
  • - Results indicated that while children with more supportive adult relationships showed lower levels of mental health problems, these protective effects were significantly reduced when accounting for genetic and environmental factors, suggesting interventions should be more multifaceted.
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Objective: Systemic lupus erythematosus (SLE) affects nine women to every man worldwide, and these patients are at greater risk for cardiovascular disease (CVD) morbidity and mortality. Clinical studies have demonstrated that patients with SLE are more likely to develop CVD, including cardiac and vascular dysfunction. Although many preclinical models of SLE are available, including treatment with Toll-like receptor (TLR) 7/8 agonists, a consistent preclinical model of SLE-like CVD with systemic, cardiac, renal, and cerebral endothelial activation and cardiac dysfunction has yet to be described.

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  • Unpaid carers play a vital role in social care, but their experiences and health outcomes differ significantly by ethnicity, according to a study using data from over 47,000 participants in the UK.
  • The research found that a higher percentage of Pakistani (70.1%) and Bangladeshi (74.8%) individuals provide care within their households compared to White individuals (39.7%).
  • Additionally, the study revealed that ethnicity influences the relationship between caring and physical health, with minority ethnic carers generally experiencing worse physical health outcomes than their White counterparts, although mental health was similarly affected across groups.
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  • The study evaluated the preparedness for and public health responses to the first two COVID-19 waves in six remote Aboriginal and Torres Strait Islander communities in Queensland.
  • Vaccination coverage varied before the first outbreak, with first doses ranging from 59% to 84% and second doses from 39% to 76%.
  • During the study, 2,624 COVID-19 cases were reported, with attack rates differing across communities and only a small number resulting in hospitalization or death.
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