Sciatic nerve injuries associated with traumatic posterior hip dislocations.

This study was undertaken to test the hypothesis that patients transferred between hospitals with a dislocated hip have a greater incidence of sciatic nerve injury than patients who have their hip reduced at the first facility. One hundred six dislocated hips were included in this 12-year retrospective study. Sixty-nine hips were relocated at the first hospital and 36 patients were transferred with the hip still dislocated to LDS Hospital.

Heterogeneity in prostacyclin and thromboxane synthesis in ovine pulmonary vascular tree: effect of age and oxygen tension.

Intrapulmonary arteries and veins of 8 near-term fetal lambs (141-145 days gestation) and 8 ewes were isolated into segments of > 3mm, 1-3 mm, and < mm in diameter. Vessels were incubated in Krebs' buffer at 37 degrees C at PO2 approximately 100 torr (normoxia) and PO2 < 50 torr (hypoxia) to study local vascular production of prostanoids. Prostacyclin and thromboxane (Tx) A2 produced were measured by radioimmunoassay and expressed in ng/mg dry wt, means +/- SEM.

Endothelin effects in isolated, perfused lamb lungs: role of cyclooxygenase inhibition and vasomotor tone.

We have determined the sites of action of endothelin-1 (ET) in the lamb pulmonary circulation. The influence of cyclooxygenase inhibition and baseline vasomotor tone on ET effects was also studied. Lungs of 14 lambs (6-9 wk of age, 12.

Segmental vascular resistance during pulsatile and steady perfusion in 3- to 5-wk-old rabbit lungs.

To determine the mechanisms by which pulsatile perfusion reduces vascular resistance in isolated lungs, we compared the effects of pulsatile versus steady perfusion on total and segmental vascular resistance in isolated lungs of 3- to 5-wk-old rabbits. Lungs were perfused alternately with steady and pulsatile flow for 45-min periods at a constant total arteriovenous pressure drop. Blood flow was adjusted to keep mean pulmonary arterial pressure at 20 cmH2O, when left atrial and airway pressures were 8 and 6 cmH2O, respectively.