Publications by authors named "R W Flint"
Brain-machine interfaces (BMIs) have advanced greatly in decoding speech signals originating from the speech motor cortices. Primarily, these BMIs target individuals with intact speech motor cortices but who are paralyzed by disrupted connections between frontal cortices and their articulators due to brainstem stroke or motor neuron diseases such as amyotrophic lateral sclerosis. A few studies have shown some information outside the speech motor cortices, such as in parietal and temporal lobes, that also may be useful for BMIs.
View Article and Find Full Text PDFIntroduction: Caffeine is the registered pharmacologic treatment for apnea of prematurity and is extensively used in the neonatal intensive care units (NICUs) based on evidence from randomized controlled trials. This study aimed to describe the clinical use of caffeine based on real-world data, hypothesizing a divergence from the registered dosing regimen.
Methods: A retrospective analysis included infants born before 30 weeks of gestation, admitted to the NICU of the Erasmus MC Rotterdam from 2018 to 2021.
Article Synopsis
- A review of cadaver studies was conducted to evaluate the decrease in compressive strength after surgery, adhering to PRISMA guidelines while utilizing databases like PubMed and Google Scholar.* -
- Out of the five studies involving 49 cadavers, one study found a statistically significant decrease in force leading to fracture (FLF) in decancellated tibias compared to the healthy ones, with a mean FLF of 3766.9 N versus 5126.4 N.* -
- Although most FLF values in the studies were significantly above the body weight threshold for safety, some cadavers recorded FLF below this threshold, suggesting that while weight-bearing after the procedure seems statistically acceptable, clinical safety cannot be universally
Introduction And Hypothesis: Identifying patient-reported outcome measures allows management of urogenital prolapse to be tailored to reflect symptom bother and expectations of treatment. We devised a new single-item questionnaire, the Patient Perception of Prolapse Condition (PPPC), based on the Patient Perception of Bladder Condition (PPBC). The aim was to evaluate the criterion validity, test/re-test reliability and responsiveness of the PPPC.
View Article and Find Full Text PDFArticle Synopsis
- Current intracortical brain-computer interfaces (iBCIs) primarily use spiking data for decoding neural activity, which can be accurate but requires high sampling rates that can be challenging to maintain.
- An alternative approach involves using local field potentials (LFPs) to capture continuous signals alongside spikes, but LFPs alone have not matched the performance of spike-based decoding.
- This study shows that by training models to use LFPs to predict firing rates from spiking data, the performance can improve significantly, allowing for lower power iBCI devices that still achieve high accuracy, even outperforming direct spike decoding in many cases.