Publications by authors named "R W Chui"
Article Synopsis
- Utilization of cangrelor as a bridging therapy to cardiac surgery has been noted for stent placement, but less so for endovascular revascularization.
- The case involves a 47-year-old female with a significant arterial dissection requiring a Viabahn endoprosthesis and subsequent cardiac procedures.
- A combination of cangrelor, aspirin, and bivalirudin was employed to manage the patient’s coronary disease and ensure the effectiveness of the surgical intervention, showcasing a multi-disciplinary approach in complex cases.
Article Synopsis
- * Numerous pyridazine-based compounds have been created to inhibit processes linked to cancer, including blockers for GLS1, TRK, and BRD, which address tumor metabolism, signaling, and epigenetics.
- * The review discusses the advancements made from 2020 to 2024 regarding pyridazine derivatives, emphasizing their structure-activity relationships and strategies for designing effective anticancer drugs.
Introduction: Advance medical directives (AMD) are statements made by individuals indicating the life-sustaining treatment that they would refuse in the future when they lost their mental capacity for medical decisions. While the proposal for the AMD legislation is ongoing locally in Hong Kong SAR, there are limited reviews on the clinical outcomes associated with it.
Objective: To provide a comprehensive review on clinical outcomes of signed AMD.
Histone deacetylase 6 (HDAC6) belongs to a class of epigenetic targets that have been found to be a key protein in the association between tumors and cardiovascular disease. Recent studies have focused on the crucial role of HDAC6 in regulating cardiovascular diseases such as atherosclerosis, myocardial infarction, myocardial hypertrophy, myocardial fibrosis, hypertension, pulmonary hypertension, and arrhythmia. Here, we review the association between HDAC6 and cardiovascular disease, the research progress of HDAC6 inhibitors in the treatment of cardiovascular disease, and discuss the feasibility of combining HDAC6 inhibitors with other therapeutic agents to treat cardiovascular disease.
View Article and Find Full Text PDFBackground: Wearable sensor technology can facilitate diagnostics and monitoring of people with upper extremity (UE) paresis after stroke. The purpose of this study is to investigate the perspectives of clinicians, people living with stroke, and their caregivers on an interactive wearable system that detects UE movements and provides feedback.
Methods: This qualitative study used semi-structured interviews relating to the perspectives of a future interactive wearable system including a wearable sensor to capture UE movement and a user interface to provide feedback as the means of data collection.