Publications by authors named "R Vu"
Clitoral metastasis from squamous cell carcinoma of the cervix on F-FDG PET/CT and MRI.
Radiol Case Rep
October 2024
Metastasis to the clitoris is extremely rare. Here, we report a highly unusual case of high-grade squamous cell carcinoma of the cervix metastasizing to the clitoris a year following surgery and chemoradiotherapy. The patient presented with a painless clitoral mass identified through physical examination.
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- Skin acts as a barrier and immune defense, with the aryl hydrocarbon receptor (AhR) playing a key role in regulating its effectiveness against external threats.
- A study reveals that OVOL1, a target of AhR in skin cells, is essential for maintaining skin barrier function and managing inflammation in atopic dermatitis (AD).
- The research suggests a new regulatory pathway involving AhR, OVOL1, and Id1 that could lead to innovative treatments for AD by enhancing skin and immune system health.
Article Synopsis
- - Skin epidermis acts as a barrier that protects against dehydration and external threats, but its mechanisms for maintaining integrity under pressure are not well understood.
- - The study shows that the removal of transcription factors Ovol1 and Ovol2 in adult skin leads to barrier breakdown, increased inflammation, and changes in immune responses, which can affect overall body metabolism.
- - Long-term effects of losing these transcription factors include failure to gain weight and fat, but these metabolic issues can be partially improved with the immunosuppressant dexamethasone, highlighting connections between skin health and wider bodily functions.
Ascending cholangitis is a clinical syndrome characterized by fever, jaundice, and abdominal pain. It is caused by stasis and infection in the biliary tract with severity ranging from mild to life threatening. The most frequent causes of biliary obstruction and ascending cholangitis are choledocholithiasis, benign biliary stricture, and obstructing malignancy.
View Article and Find Full Text PDFHabitat fragmentation is an important driver of biodiversity loss and can be remediated through management actions aimed at maintenance of natural connectivity in metapopulations. Connectivity may protect populations from infectious diseases by preserving immunogenetic diversity and disease resistance. However, connectivity could exacerbate the risk of infectious disease spread across vulnerable populations.
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