Publications by authors named "R Virgilio"
Rhabdomyolysis is a relatively rare condition caused by the damage and release of myocyte contents. It occurs most commonly secondary to strenuous exercise. Rhabdomyolysis carries the risk of life-threatening negative sequelae such as acute kidney injury or death.
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- Duchenne muscular dystrophy (DMD) is a progressive genetic disorder that currently has no cure, and its management relies on physiotherapy and medications to slow progression.
- Gene therapy presents a promising treatment option but requires a well-organized delivery system, such as the hub-and-spoke model, to effectively support DMD patients in Italy.
- A study mapped existing DMD centers in Italy, evaluated their readiness for gene therapy, and identified areas for improvement, ultimately proposing a flexible organizational model to enhance patient care.
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- * A 63-year-old male with CES symptoms—urinary and fecal retention, and altered genital sensation—was found to have metastatic lesions in his sacral spine and a primary lung lesion indicated by CT and MRI scans.
- * The patient was diagnosed with metastatic neuroendocrine carcinoma after a lymph node biopsy and underwent treatment including steroids, chemotherapy, and radiation, highlighting the need for thorough evaluation for metastasis in CES cases.
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- - Acute transverse myelitis (TM) is a rare spinal cord disorder characterized by symptoms like motor weakness, sensory changes, and bowel or bladder dysfunction, affecting mostly younger and middle-aged adults, although this case involves a 72-year-old male.
- - The patient, with a history of hypertension and type 2 diabetes, presented with upper extremity weakness and new abdominal numbness after a trip to a theme park, leading to a diagnosis of TM confirmed by MRI and lumbar puncture.
- - The patient's TM was linked to newly diagnosed Sjögren's autoimmune disease, and although he was treated with intravenous steroids, he was readmitted due to poor adherence to discharge instructions, highlighting the need for quick recognition and treatment to prevent further
A 13-year-old male with a past medical history of receiving a whole liver transplant secondary to alpha-1 antitrypsin deficiency (AATD) with subsequent inferior vena cava thrombosis nine years prior presented to the emergency department with abdominal distension, shortness of breath, coughing, and left superficial cervical lymphadenopathy. He had seen his pediatrician the day before where he tested negative for group A , influenza, and severe acute respiratory syndrome coronavirus 2. Additionally, the patient reported having elevated liver function tests noted from the results of lab tests taken earlier that day.
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