Publications by authors named "R Videbaek"

Article Synopsis
  • The Danish Study (DANISH) aimed to evaluate the impact of implantable cardioverter-defibrillators (ICD) on health-related quality of life (HRQoL) in patients with non-ischaemic systolic heart failure, despite finding no overall effect on mortality.
  • In the study, 1116 patients were randomly assigned to receive either ICD implantation or standard care, with HRQoL assessed using the Minnesota Living with Heart Failure Questionnaire (MLHFQ) over 8 months.
  • Results indicated that there were no significant differences in HRQoL improvements between the ICD group and the control group, suggesting that ICD implantation did not enhance quality of life for these patients.
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Background: The DANISH study (Danish Study to Assess the Efficacy of ICDs [Implantable Cardioverter Defibrillators] in Patients With Non-Ischemic Systolic Heart Failure on Mortality) did not demonstrate an overall effect on all-cause mortality with ICD implantation. However, the prespecified subgroup analysis suggested a possible age-dependent association between ICD implantation and mortality with survival benefit seen only in the youngest patients. The nature of this relationship between age and outcome of a primary prevention ICD in patients with nonischemic systolic heart failure warrants further investigation.

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Article Synopsis
  • The study investigated the impact of implantable cardioverter-defibrillators (ICDs) on patients with symptomatic systolic heart failure not caused by coronary artery disease, comparing ICD treatment with usual clinical care.
  • A total of 1,116 patients were enrolled, and after 67.6 months, it was found that ICDs did not significantly lower overall mortality rates compared to the control group, although they did reduce instances of sudden cardiac death.
  • The findings suggest that while ICDs may have benefits for sudden cardiac death prevention, they do not significantly improve long-term survival rates in this specific patient population.
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Background: Little systematic evidence is available on potential gender differences in patients with an implantable cardioverter defibrillator (ICD) from a real-world cohort. We designed the DEFIB-WOMEN (The Utilization of Implantable Cardioverter DEFIBrillator Therapy in the Treatment of Heart Disease: Clinical and Psychological outcomes in WOMEN) study to examine gender differences on (1) patient-reported outcomes (PROs), (2) procedure- and device-related complications, and (3) ventricular tachyarrhythmia and mortality. This presents the study design and baseline characteristics of the cohort.

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Objective: Cardiovascular implantable electronic device (CIED) infections are increasing in numbers. The objective was to review the clinical presentation and outcome in patients affected with CIED infections with either local pocket or systemic presentation.

Design: All device removals due to CIED infection during the period from 2005 to 2012 were retrospectively reviewed.

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