Publications by authors named "R Vibo"
Article Synopsis
- * Researchers collected blood samples from 73 patients and analyzed the expression of specific genes and miRNAs using real-time quantitative PCR, revealing significant differences in gene expression patterns between the two types of stroke.
- * Findings showed that certain inflammatory genes were more upregulated during the acute phase of cryptogenic stroke compared to LAA stroke, suggesting differing inflammatory responses associated with these two stroke types.
Background: Monitoring and measuring different aspects of stroke care pathway is the cornerstone for improvement of quality. We aim to analyze and give an overview of improvements of stroke care quality in Estonia.
Patients And Methods: National stroke care quality indicators are collected and reported using reimbursement data and include all adult stroke cases.
Background: Behavioral risk factors are common among young patients with stroke. This study aimed to compare the health behavior of patients and healthy controls and develop a combined risk score of health behavior.
Methods: The health behavior of patients aged 18-54 years who suffered an ischemic stroke from 2013 to 2020 in Estonia was compared to the Health Behavior among Estonian Adult Population 2014 study sample.
Previous genome-wide association studies (GWASs) of stroke - the second leading cause of death worldwide - were conducted predominantly in populations of European ancestry. Here, in cross-ancestry GWAS meta-analyses of 110,182 patients who have had a stroke (five ancestries, 33% non-European) and 1,503,898 control individuals, we identify association signals for stroke and its subtypes at 89 (61 new) independent loci: 60 in primary inverse-variance-weighted analyses and 29 in secondary meta-regression and multitrait analyses. On the basis of internal cross-ancestry validation and an independent follow-up in 89,084 additional cases of stroke (30% non-European) and 1,013,843 control individuals, 87% of the primary stroke risk loci and 60% of the secondary stroke risk loci were replicated (P < 0.
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