Publications by authors named "R Veteikis"

Monitoring and control of the heart tissue viability is of crucial importance during heart surgery operations. In most cases the heart tissue suffers from an ischemic injury that causes a decrease in the velocity of electrical excitation propagation in it and influences the shape of the excitation wave front that spreads over the injured area. It is reflected in a more complex shape of the registered epicardial electrogram as compared to normal.

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Connexins (Cx) form intercellular junctional channels which are responsible for metabolic and electrical coupling. We report here on the biochemical and immunohistochemical characterization of zebrafish connexin zfCx43.4, an orthologue of mammalian and avian Cx45, and the electrophysiological properties of junctional channels formed by this protein.

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The distribution of the electronic potential in the endocardium and epicardium of the rabbit right atrium was studied. The distribution of the electronic potential was studied by the method of intracellular polarization of cardiac fibers via a suction electrode perfused from the inside with a KCl isotonic solution. The space constant of electronic decay along and across cardiac fibers in the endocardium and epicardium of rabbit right atrium was measured.

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The work was centered on theoretical investigation of the spread of electrotonic potential in the cardiac tissue during the delivery of long-term rectangular pre-threshold current impulses to the tissue. A mathematical model of two-dimensional anisotropic medium, with a circumference-shaped current source, has been developed. In accordance with the superposition principle well-known in electrostatics, the source of current was approximated by point sources placed on the perimeter of the current source in two ways: 1) by regular division of the perimeter of the current source in metric coordinate system, 2) by regular division of the perimeter of current source in the normalized coordinate system.

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The effect of acetylcholine (ACH) on passive electric properties and intercellular coupling was studied using microelectrode technique in experiments on isolated preparations of the sinoatrial area of the rabbit's heart. The space constant of electrotonic decay (lambda delta) and input resistance (RBX) were measured. ACH was found to reduce lambda delta and increase RBX.

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