Publications by authors named "R Vanleyssem"

Article Synopsis
  • Transfer RNA (tRNA) dynamics play a significant role in cancer by influencing how messenger RNA (mRNA) translates into proteins, specifically through aminoacyl-tRNA synthetases that can either encourage or inhibit tumor growth.
  • Research indicates that valine aminoacyl-tRNA synthetase (VARS) is crucial for the changes in protein translation related to resistance against MAPK therapy in melanoma patients, as there is an increased use of valine in their proteomes.
  • Additionally, reducing VARS levels can make MAPK-resistant melanoma cells more sensitive to treatment, as VARS is linked to the translation of key mRNAs that support cell survival via fatty acid oxidation.
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This study assessed the bioprotective effect of Carnobacterium maltaromaticum (CM) against Pseudomonas fluorescens (PF) and Brochothrix thermosphacta (BT) in ground beef and sliced cooked ham stored in high- and low-oxygen-modified atmospheres (66/4/30% O/N/CO and 70/30% N/CO respectively). Both meat products were inoculated with CM, PF, and BT individually or in combination and stored for 7 days (3 days at 4 °C + 4 days at 8 °C) for ground beef and 28 days (10 days at 4 °C + 18 days at 8 °C) for sliced cooked ham. Each food matrix was assigned to 6 treatments: NC (no bacterial inoculation, representing the indigenous bacteria of meat), CM, BT, PF, CM + BT, and CM + PF.

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Outgrowth and toxinogenesis of Clostridium botulinum Group II (non-proteolytic) type B were studied in cooked ham prepared with different NaNO (ranging from 0 to 80 mg/kg) and sodium chloride (NaCl, ranging from 12 to 19 g/kg) incorporation rates. Cured ground pork batters were inoculated with a cocktail of 3 strains of C. botulinum Group II type B at 3.

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In recent years, several studies have described the presence of Clostridium difficile in healthy and diarrhoeic farm and domestic animals. In pigs and cattle, the isolation of some PCR-ribotypes associated with human infection, especially PCR-ribotypes 014 and 078, has led us to hypothesize about the zoonotic transmission of C. difficile infections.

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