[Frequency of glomerular diseases in an analysis of 550 kidney biopsies].

Background: The frequency of glomerular diseases is dynamic and varies according to geographic area.

Aim: To evaluate the frequency of primary and secondary glomerulopathies, their demographic profile and main clinical characteristics.

Material And Methods: Renal biopsies from native kidneys performed between 1999 and 2020 were retrospectively reviewed.

[Late-onset hereditary transthyretin amyloidosis with polyneuropathy. Report of one case].

Hereditary transthyretin amyloidosis is a multisystemic autosomal dominant genetic disorder characterized by progressive distal sensory-motor polyneuropathy or restrictive cardiomyopathy, secondary to amyloid deposits. Its pathogenesis lies in the TTR gene mutation, and the Val50Met mutation is the most frequent. Patients have significant differences in the onset and severity of clinical presentation according to their country of origin.

Identifying Factors Predicting Kidney Graft Survival in Chile Using Elastic-Net-Regularized Cox's Regression.

: We developed a predictive statistical model to identify donor-recipient characteristics related to kidney graft survival in the Chilean population. Given the large number of potential predictors relative to the sample size, we implemented an automated variable selection mechanism that could be revised in future studies as more national data is collected. : A retrospective multicenter study was conducted to analyze data from 822 adult kidney transplant recipients from adult donors between 1998 and 2018.

AL amyloidosis in the Chilean public health system: a pending debt. Multicenter study of the Chilean Monoclonal Gammopathies Cooperative Group.

Background: Immunoglobulin light chain (AL) amyloidosis is a rare and underdiagnosed entity.

Aim: To characterize patients with AL amyloidosis in Chilean public health centers.

Material And Methods: We conducted a retrospective, multicenter study.