Histopathology of experimental systemic candidosis in guinea-pigs.

Unpretreated Albino guinea-pigs were infected intravenously with Candida albicans. Cutaneous candidosis with (pseudo-) hyphal outgrowth in the hair shafts and in the keratinized layers of the epidermis developed as a consequence of systemic dissemination. The spread of the infection was followed by cultures and by gross- and micropathological study of various organs of different animals during a follow-up period of 35 days.

A comparison between manual and semiautomatic white cell differentiation.

Manual and semiautomatic white cell differentiations have been found to produce comparable results. Semiautomatic counting can be accomplished with a smaller number of cells than required in manual counting without significant loss of accuracy. Cell types have been compared one by one to detect systematic deviations between the counting procedures.